Description
LY-83583 is an inhibitor of soluble guanylate cyclase and of cGMP production. It inhibits soluble guanylate cyclase in human platelets with an IC₅₀ value of 2 µM. Also blocks the release of intracellular Ca²⁺ and antigen-induced leukotrienes.
LY-83583 is an inhibitor of soluble guanylate cyclase and of cGMP production. It inhibits soluble guanylate cyclase in human platelets with an IC₅₀ value of 2 µM. Also blocks the release of intracellular Ca²⁺ and antigen-induced leukotrienes.
Alternate Name/Synonyms: 6-(phenylamino)-5,8-quinolinedione
Appearance: Violet solid
Formulation: N/A
CAS Number: 91300-60-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₅H₁₀N₂O₂
Molecular Weight: 250.25
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: An inhibitor of soluble guanylate cyclase and of cGMP production
MDL Number: MFCD00210756
PubChem CID: 3976
SMILES: C1=CC=C(C=C1)NC2=CC(=O)C3=C(C2=O)C=CC=N3
InChi: InChI=1S/C15H10N2O2/c18-13-9-12(17-10-5-2-1-3-6-10)15(19)11-7-4-8-16-14(11)13/h1-9,17H
InChi Key: GXIJYWUWLNHKNW-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |