Description
LY2811376 is a BACE1 inhibitor with marked Ab-lowering effects in animal models.
LY2811376 is a BACE1 inhibitor with marked Ab-lowering effects in animal models.
Alternate Name/Synonyms: LY 2811376, LY-2811376, BACE-1 Inhibitor, (4S)-4-(2,4-difluoro-5-pyrimidin-5-ylphenyl)-4-methyl-5,6-dihydro-1,3-thiazin-2-amine
Appearance: Solid
Formulation: N/A
CAS Number: 1194044-20-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₅H₁₄F₂N₄S
Molecular Weight: 320.36
Cell-Permeable?: Yes
Purity: 99.88% by LCMS
Solubilities: DMSO: >31 mg/ml
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A BACE1 inhibitor with marked Ab-lowering effects in animal models.
MDL Number: MFCD18074525
PubChem CID: 44251605
SMILES: CC1(CCSC(=N1)N)C2=C(C=C(C(=C2)C3=CN=CN=C3)F)F
InChi: 1S/C15H14F2N4S/c1-15(2-3-22-14(18)21-15)11-4-10(12(16)5-13(11)17)9-6-19-8-20-7-9/h4-8H,2-3H2,1H3,(H2,18,21)/t15-/m0/s1
InChi Key: MJQMRGWYPNIERM-HNNXBMFYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |