LY86 polyclonal Antibody | BS7951

LY86 polyclonal Antibody | BS7951 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB IHC

Application Range: WB: 1:500~1:2000 IHC: 1:50~1:200

Background: RP105 (CD180) was originally discovered as a mouse B cell surface molecule that transmits an activation signal. This signal leads to resistance against irradiation-induced apoptosis and massive B cell proliferation. RP105 is associated with another molecule, MD-1, which has an important role in the cell surface expression of RP105. MD-1, also known as lymphocyte antigen 68 and RP105 associated protein, associates with and regulates the cell surface expression of RP105. RP105/MD-1 constitutes an LPS-signaling complex on B cells and, like MD-2, enhances the LPS signaling via TLR4. MD-1 contains 162 amino acids and has a predicted 19 amino acid signal peptide and 2 N-glycosylation sites. MD-1 is highly expressed in B cells, monocytes and tonsil, and is localized on the surface of cells despite its lack of a transmembrane region.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: LY86 polyclonal Antibody detects endogenous levels of LY86 protein.

Molecular Weight: ~ 24 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: BPAD; dJ80N2.1; Ly 86; Ly-86; LY86; LY86_HUMAN; Lymphocyte antigen 86; Lymphocyte antigen 86 precursor; Major affective disorder 1; MD 1; MD1 protein; MD1 RP105 associated; MD1 RP105 associated; MMD 1; Protein MD 1; Protein MD-1; RP1-80N2.1;

Immunogen: Recombinant full length Human LY86.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: