M-CSF, murine recombinant | 4238

Macrophage Colony stimulating Factor (M-CSF) is produced by various cell types, including fibroblasts, microphages, and endothelial cells. M-CSF is involved in both the development and function of monocytes/microphages. The recombinant M-CSF is a disulfide-linked homodimer composed of two 18.2 kDa subunits of 156 amino acid residues.

4238 | M-CSF murine recombinant DataSheet

Biomolecule/Target: M-CSF

Synonyms: Macrophage Colony Stimulating Factor, CSF-1, MGI-IM

Alternates names: OSM, MGC20461.

Taglines: A hematopoietic growth factor

NCBI Gene ID #: 5008

NCBI Gene Symbol: OSM

Gene Source: Human

Accession #: P13725

Recombinant: Yes

Source: Human 293 cell expressed

Purity by SDS-PAGEs: > 95%

Assay: SDS-PAGE

Purity: 98%

Assay #2: HPLC

Endotoxin Level: < 1.0 EU per 1 g of protein

Activity (Specifications/test method): N/A

Biological activity: ED is typically 2 to 10 ng/mL. The specific activity was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).

Results: 2 to 10 ng/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 30 kDa, monomer, glycosylated

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Sterile filtered and then lyophilized from 5 mM Tris, pH 8.0 + 100 mM NaCl.

Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

Amino acid sequence: N/A