MANF Polyclonal Antibody | E-AB-12987

MANF Polyclonal Antibody | E-AB-12987 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Arginine rich mutated in early stage tumors, Arginine rich protein, Arginine-rich protein, ARMET, ARMET protein, ARP, Manf, MANF, Mesencephalic astrocyte derived neurotrophic factor, Mesencephalic astrocyte-derived neurotrophic factor, MGC142148, MGC142150, Protein ARMET

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Neuroscience

Background: The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.

Concentration: 0.1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human MANF

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:100-1:300

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A