LBD
MAP4K1 (HPK1) Antibody (C-term) [APR17291G]
- SKU:
- LBD-APR17291G
- Availability:
- Usually ships in 5 working days
Description
MAP4K1 (HPK1) Antibody (C-term) [APR17291G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This MAP4K1 (HPK1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 321-350 amino acids from the C-terminal region of human MAP4K1 (HPK1) .
Cellular Localisation: N/A
Molecular Weight: 91296
Clone: Polyclonal
Gene Name: MAP4K1
Gene ID: 11184
Function: Serine/threonine-protein kinase, which may play a role in the response to environmental stress (PubMed:24362026) . Appears to act upstream of the JUN N-terminal pathway (PubMed:8824585) . May play a role in hematopoietic lineage decisions and growth regulation (PubMed:8824585, PubMed:24362026) . Able to autophosphorylate (PubMed:8824585) . Together with CLNK, it enhances CD3-triggered activation of T-cells and subsequent IL2 production (By similarity) .
Summary: Tissue Location: Expressed primarily in hematopoietic organs, including bone marrow, spleen and thymus. Also expressed at very low levels in lung, kidney, mammary glands and small intestine
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P
Dilution: WB--1:1000 IHC-P--1:100~500
Synonyms: Mitogen-activated protein kinase kinase kinase kinase 1, Hematopoietic progenitor kinase, MAPK/ERK kinase kinase kinase 1, MEK kinase kinase 1, MEKKK 1, MAP4K1, HPK1