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MARCKSL1 polyclonal Antibody | BS60523
- SKU:
- BW-BS60523
- Availability:
- Usually ships in 5 working days
Description
MARCKSL1 polyclonal Antibody | BS60523 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB: 1:500~1:1000
Background: MARCKS (Myristoylated alanine-rich protein kinase C substrate), also designated 80K or 80K-L, is a 332 amino acid protein that localizes to the plasma membrane and functions as a major cellular substrate for protein kinase C (PKC) . MARCKSL1 (MARCKS-like protein 1), also known as MacMARCKS, MLP, MRP, or F52, is a 195 amino acid protein that, like MARCKS, is a major substrate for PKC. Expressed in a variety of tissues with highest levels found in testis and uterus, MARCKSL1 participates in the coordination of membrane-cytoskeletal signaling events, including secretion, migration, phagocytosis and cell adhesion. Additionally, MARCKSL1 functions as a regulator of Integrin activation and is thought to regulate Integrin-dependent signal transduction pathways, especially those involved in macrophage spreading.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: MARCKSL1 polyclonal Antibody detects endogenous levels of MARCKSL1 protein.
Molecular Weight: ~ 20 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: MARCKS-related protein; MARCKS-like protein 1; Macrophage myristoylated alanine-rich C kinase substrate; Mac-MARCKS; MacMARCKS
Immunogen: A synthetic peptide corresponding to residues in Human MARCKSL1
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: