MaxiKβ (K119) polyclonal Antibody | BS3554

MaxiKβ (K119) polyclonal Antibody | BS3554 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: IHC

Application Range: IHC:1:50~1:200

Background: MaxiK channels are large conductance voltage and Ca 2+-activated potassium channels which are formed by tetramers of MaxiKα subunits, which create pores that are used for smooth muscle tone and neuronal excitability. These MaxiKα subunits have the ability to coassemble with MaxiKβ subunits that are structurally related and are able to regulate the function of MaxiKα subunits. KCNMB4 (potassium large conductance calcium-activated channel, subfamily M, β member 4), also known as Slo-β-4 or Maxi K channel subunit β-4, is a 210 amino acid multi-pass membrane protein belonging to the KCNMB family. Predominantly expressed in brain, KCNMB4 is a regulatory subunit of the calcium activated potassium MaxiKα channel. KCNMB4 contributes to MaxiKα channel diversity by modulating calcium sensitivity and gating kinetics of MaxiKα.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MaxiKβ (K119) polyclonal Antibody detects endogenous levels of MaxiKβ protein.

Molecular Weight: ~ 24 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Calcium-activated potassium channel subunit beta-4; BK channel subunit beta-4; BKbeta4; Hbeta4; Calcium-activated potassium channel; subfamily M subunit beta-4; Charybdotoxin receptor subunit beta-4; K (VCA) beta-4; Maxi K channel subunit beta-4; Slo-beta-4; KCNMB4

Immunogen: Synthetic peptide, corresponding to amino acids 86-140 of Human MaxiKβ.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: