Description
MC-1568 is a selective class II (IIa) histone deacetylase (HDAC II) inhibitor (IC₅₀ = 220 nM). It displays >170-fold selectivity over class I HDACs, including HDAC1.
MC-1568 is a selective class II (IIa) histone deacetylase (HDAC II) inhibitor (IC₅₀ = 220 nM). It displays >170-fold selectivity over class I HDACs, including HDAC1.
Alternate Name/Synonyms: 3-[5-(3-(3-Fluorophenyl)-3-oxopropen-1-yl)-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-2-propenamide
Appearance: White solid
Formulation: N/A
CAS Number: 852475-26-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₇H₁₅FN₂O₃
Molecular Weight: 314.31
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>30 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent and specific inhibitor of class II histone deacetylases (HDACs)
MDL Number: MFCD16875423
PubChem CID: 11381449
SMILES: CN1C=C(C=C1C=CC(=O)NO)C=CC(=O)C2=CC(=CC=C2)F
InChi: InChI=1S/C17H15FN2O3/c1-20-11-12(9-15(20)6-8-17(22)19-23)5-7-16(21)13-3-2-4-14(18)10-13/h2-11,23H,1H3,(H,19,22)/b7-5+,8-6+
InChi Key: QRDAPCMJAOQZSU-KQQUZDAGSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |