MCP-1 (MCAF), human recombinant | 4222

Monocyte Chemoattractant Protein 1 (MCP-1), also known as CCL2, is thought to be produced by injured or infected tissues. MCP-1 signals through G protein-coupled receptors, CCR2 and CCR4, to recruit memory T cells, monocytes and dendritic cells. Recombinant mouse MCP-1 is a non-glycosylated protein, containing 76 amino acids and having a molecular mass of 8.6 kDa.

4222 | MCP-1 MCAF human recombinant DataSheet

Biomolecule/Target: MCP-1/CCL2

Synonyms: MCP1, SCYA2

Alternates names: CTLA-8, IL-17, IL-17A, Cytotoxic T-lymphocyte-associated antigen 8.

Taglines: Chemoattractant for monocytes and basophils

NCBI Gene ID #: 3605

NCBI Gene Symbol: IL17A

Gene Source: Human

Accession #: Q16552

Recombinant: Yes

Source: Human 293 cell expressed

Purity by SDS-PAGEs: > 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: < 1.0 EU per 1 g of protein

Activity (Specifications/test method): N/A

Biological activity: ED is typically 5 to 25 ng/mL. The specific activity was determined by the dose-dependent induction of IL-6 secretion from NDHF Adult fibroblasts.

Results: 5 to 25 ng/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 30 to 35 kDa, homodimer, glycosylated

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Sterile filtered and lyophilized with no additives

Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

Amino acid sequence: N/A