MCP-3/CCL7, rat recombinant | 4230

Monocyte Chemotactic Protein 3 (MCP-3), also called CCL7, is chemokine produced by macrophages and some tumor cell lines. MCP-3 signals through three different G protein-coupled receptors, CCR1, CCR2, and CCR3. CCL7 chemoattracts monocytes and can regulate macrophage function. Recombinant rat MCP-3 is a non-glycosylated protein, containing 75 amino acids, with a molecular weight of 8.6 kDa.

4230 | MCP-3/CCL7 rat recombinant DataSheet

Biomolecule/Target: MCP-3

Synonyms: CCL7, MARC

Alternates names: Interleukin-29, IL-29, IFN-Lambda 1, Interferon-Lambda 1, Cytokine ZCYTO21, IL29, IFNL1, ZCYTO21.

Taglines: Chemoattractant for monocytes

NCBI Gene ID #: 282618

NCBI Gene Symbol: IFNL1

Gene Source: Human

Accession #: Q8IU54

Recombinant: Yes

Source: Human 293 cell expressed

Purity by SDS-PAGEs: > 95%

Assay: SDS-PAGE

Purity: 97%

Assay #2: HPLC

Endotoxin Level: < 1.0 EU per 1 g of protein

Activity (Specifications/test method): N/A

Biological activity: ED is typically 0.5 to 5 ng/mL. The specific activity was determined by the dose-dependent protection of the cytopathic effect on A549 cells (human lung adenocarcinoma epithelial cell line) that were challenged with encephalomyocarditis (EMC) virus.

Results: 0.5 to 5 ng/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 29 and 35 kDa, monomer, glycosylated

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Sterile filtered and lyophilized with no additives

Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

Amino acid sequence: N/A