MCP-5/CCL12, murine recombinant | 7168

The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross- reacts across species. Recombinant murine MCP-5 is a 9.3 kDa protein containing 82 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

7168 | MCP-5/CCL12 murine recombinant DataSheet

Biomolecule/Target: CCL12

Synonyms: Monocyte Chemotactic Protein-5, CCL12

Alternates names: SYM1, SYNS1, NOG.

Taglines: Chemoattracts / activates monocytes, activated T cells, basophils, NK cells, and immature dendritic cells

NCBI Gene ID #: 9241

NCBI Gene Symbol: NOG

Gene Source: Human

Accession #: Q13253

Recombinant: Yes

Source: Human 293 cell expressed

Purity by SDS-PAGEs: > 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: < 1.0 EU per 1 g of protein

Activity (Specifications/test method): N/A

Biological activity: ED is typically 20 to 100 ng/mL. The specific activity was determined by the dose-dependent inhibition of rhBMP4 induced alkaline phosphate production by ATDC5 cells.

Results: 20 to 100 ng/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 65 kDa, homodimer, glycosylated

Concentration: N/A

Appearance: Lyophilized powder

Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.

Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

Amino acid sequence: N/A