MCT2 polyclonal Antibody | BS65535

MCT2 polyclonal Antibody | BS65535 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Mouse, Rat

Application: WB,

Application Range: WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

Background: Tissues with few or no mitochondria, such as erythrocytes and tumor cells, depend largely on glycolysis to generate ATP. The major end products of glycolysis, pyruvate and lactate, must be eliminated from these cells to enable continued glycolytic flux and prevent toxic effects. H+/monocarboxylate transporters (MCTs) mediate the transport of lactate and pyruvate. Human MCT2 has a high affinity for the transport of pyruvate (summary by Lin et al., 1998 [PubMed 9786900]) .[supplied by OMIM, Feb 2011].

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MCT2 polyclonal Antibody detects endogenous levels of MCT2 protein.

Molecular Weight: ~50kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: MCT 2; MCT; Monocarboxylate transporter 2; MonocarboxylateTransporter 2; MOT2; MOT2_HUMAN; SLC16A7; Solute carrier family 16 member 7; Solute carrier Family 16 Monocarboxylic Acid Transporters Member 7.

Immunogen: KLH conjugated synthetic peptide derived from mouse MCT2 :411-478/478

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: