MDH1 polyclonal Antibody | BS60457

MDH1 polyclonal Antibody | BS60457 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Cytosolic malate dehydrogenase (MDHC or cMDH) is an important NAD-dependent enzyme involved in glycometabolism that catalyzes the formation of oxaloacetate and NADH from L-malate and NAD. MDHC is highly expressed in brain, heart and skeletal muscle and plays a role in aerobic energy production for muscle contraction, transmission of neuronal signals, absorption/ resorption pathways, collagen-supporting functions, dead cell phagocytosis, as well as pathways involved in gas exchange and cell division. Furthermore, MDHC is a regulatory subunit of the nucleic acid-conducting channel (NACh) . MDHC functions as a homodimer and is highly conserved in plants, animals and bacteria. The activity of MDHC is controlled by the sesquiterpenoid juvenile hormone (JH) and the steroid hormone ecdysone.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MDH1 polyclonal Antibody detects endogenous levels of MDH1 protein.

Molecular Weight: ~ 36 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Malate dehydrogenase, cytoplasmic; Cytosolic malate dehydrogenase; Diiodophenylpyruvate reductase; MDHA; MDHC; cMDH

Immunogen: A synthetic peptide corresponding to residues in Human MDH1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Phospholipase Signaling,Immune Cell Signaling,Toll-like Receptor signaling,B cell receptor signaling,MAPK Erk in Growth and Differentiation Pathway,