Meglumine | B3036

Meglumine is a derivative of sorbitol in which the hydroxyl group in position 1 is replaced by a methylamino group. It is used as an excipient for drug formulations and for preparing salts. The meglumine or combined meglumine-sodium salts of triiodinated benzoic acid derivatives, diatrizoic and iothalamic acid, are commonly used as intravascular ionic contrast media for radiographic visualization of blood vessels and the urinary tract. Meglumine salts of iodoxamate and iodipamide are also used for intravenous cholangiography. Meglumine shows protective effects in Type II Diabetes. It significantly improves glycemic control and lowers levels of plasma and liver triglycerides in a mice model of type 2 Diabetes.

Meglumine is a derivative of sorbitol in which the hydroxyl group in position 1 is replaced by a methylamino group. It is used as an excipient for drug formulations and for preparing salts. The meglumine or combined meglumine-sodium salts of triiodinated benzoic acid derivatives, diatrizoic and iothalamic acid, are commonly used as intravascular ionic contrast media for radiographic visualization of blood vessels and the urinary tract. Meglumine salts of iodoxamate and iodipamide are also used for intravenous cholangiography. Meglumine shows protective effects in Type II Diabetes. It significantly improves glycemic control and lowers levels of plasma and liver triglycerides in a mice model of type 2 Diabetes.

B3036 | Meglumine DataSheet

Alternate Name/Synonyms: N-Methyl-D-glucamine; Meglumin; (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol; 1-Deoxy-1-(methylamino)-D-glucitol; 1-Deoxy-1-methylaminosorbitol

Appearance: White to Off-White Solid

Formulation:

CAS Number: 6284-40-8

Structure Available?: TRUE

Peptide sequence:

Salt Form: FALSE

Molecular Formula: C₇H₁₇NO₅

Molecular Weight: 195.21

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: ~12 mg/ml in water, ~39 mg/ml in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A derivative of sorbitol used as an excipient

MDL Number: MFCD00004707

PubChem CID: 8567

SMILES: CNCC(C(C(C(CO)O)O)O)O

InChi: InChI=1S/C7H17NO5/c1-8-2-4(10)6(12)7(13)5(11)3-9/h4-13H,2-3H2,1H3/t4-,5+,6+,7+/m0/s1

InChi Key: MBBZMMPHUWSWHV-BDVNFPICSA-N