Additional Information
Size: |
100 µl |
Target: |
MEK1 + MEK2 (pSer218/222) |
Conjugate: |
FITC |
Research Area: |
Cell Signaling | Protein Phosphorylation | Tyrosine Kinases | Cell Signaling | Protein Phosphorylation | Serine / Threonine Kinases | MAPK Pathway |
Alternative Name: |
MAP kinase/Erk kinase 1 Antibody, MKK 1 Antibody, ERK activator kinase 1 Antibody, MAPK/ERK kinase 1 Antibody, MEK1 Antibody, MEKK1 Antibody, MKK1 Antibody, EC:2.7.12.2 Antibody, MAP2K1 Antibody, Dual specificity mitogen-activated protein kinase kina |
Category: |
Antibodies |
Product Type: |
Polyclonal Antibody |
Immunogen: |
Synthetic phospho-peptide from human MEK1 + MEK2 proteins around the phosphorylation sites of MEK1 at serine 218 (pSer218) and MEK2 at serine 222 (pSer222). |
Immunogen Species: |
Human |
Applications: |
WB |
Host: |
Rabbit |
Isotype: |
IgG |
Species Reactivity: |
Human, Mouse, Rat |
Antibody Dilution: |
WB (1:500-1500); optimal dilutions for assays should be determined by the user. |
Purification: |
Peptide Affinity Purified |
Storage Buffer: |
PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide |
Concentration: |
N/A |
Specificity: |
Detects endogenous levels of MEK1 only when phosphorylated at serine 218 (pSer218) and MEK2 only when phosphorylated at serine 222 (pSer222). Detects ~ 45 kDa. Detects a band at ~45 kDa. |
Storage: |
-20ºC |
Shipping: |
Blue Ice or 4ºC |
Certificate of Analysis: |
N/A |
Cellular Localization: |
Cytoskeleton, Centrosome, Spindle Pole Body, Nucleus, Cytoplasm Membrane, Peripheral Membrane Protein, Cytoplasm, Membrane, Microtubule Organizing Center, Cytosol, Endoplasmic Reticulum, Endosome, Early Endosome, Late Endosome, Extracellular Exosome, |
Tissue Specificity: |
Widely expressed, with extremely low levels in brain. |
Accession Number: |
NP_002746.1/NP_109587.1 |
Gene ID: |
5604/5605 |
Swiss-Prot: |
Q02750/P36507 |
Field of Use: |
For in vitro research use only. |