MEK3/6 polyclonal Antibody | BS90841

MEK3/6 polyclonal Antibody | BS90841 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC/IF IHC IP FC

Application Range: WB:1:1,000-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100

Background: A family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: MEK3/6 polyclonal Antibody detects endogenous levels of MEK3/6 protein.

Molecular Weight: 39/37 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: MAP kinase kinase 3, MAPKK 3, MEK 3, SAPK kinase 2, SAPKK-2, SAPKK2, MAP2K3, MAP kinase kinase 6, MAPKK 6, MEK 6, SAPK kinase 3, SAPKK-3, SAPKK3, MAP2K6, Dual specificity mitogen activated protein kinase kinase 6, Dual specificity mitogen-activated protein kinase kinase 3, MAP kinase kinase 3, MAP kinase kinase 6, map2k3, MAP2K6, MAPK/ERK kinase 3, MAPK/ERK kinase 6, MAPKK 3, MAPKK 6, MAPKK3, MAPKK6, MEK 3, MEK 6, Mitogen activated protein kinase kinase 3, Mitogen activated protein kinase kinase 6, MKK3, MKK6, MP2K3, PRKMK3, PRKMK6, Protein kinase, mitogen activated, kinase 6 (MAP kinase kinase 6), SAPK kinase 2, SAPKK 3, SAPKK-2, SAPKK2, SAPKK3, Stress activated protein kinase kinase 3, Stress-activated protein kinase kinase 2,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: