MEK3 polyclonal Antibody | BS90840

MEK3 polyclonal Antibody | BS90840 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Application: WB ICC/IF IHC IP FC

Application Range: WB:1:1,000-1:5,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100

Background: A family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: MEK3 polyclonal Antibody detects endogenous levels of MEK3 protein.

Molecular Weight: 39 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: MAP kinase kinase 3, MAPKK 3, MEK 3, SAPK kinase 2, SAPKK-2, SAPKK2, MAP2K3, AW212142, dual specificity mitogen activated protein kinase kinase 3, Dual specificity mitogen-activated protein kinase kinase 3, MAP kinase kinase 3, map2k3, MAPK ERK kinase 3, MAPK/ERK kinase 3, MAPKK 3, MAPKK3, MEK 3, MEK3, Mitogen activated protein kinase kinase 3, MKK 3, MKK3, mMKK3b, MP2K3, PRKMK 3, PRKMK3, protein kinase, mitogen-activated, kinase 3, SAPK kinase 2, SAPKK 2, SAPKK2, Stress activated protein kinase kinase 2,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: