Description
MEPCE polyclonal Antibody | BS8724 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human
Application: WB IF
Application Range: WB: 1:500~1:2000 IHC: 1:50~1:200 IF: 1:50~1:200
Background: BCDIN3 (bicoid-interacting protein 3), also known as MEPCE (methylphosphate capping enzyme), is a 689 amino acid protein that contains one BIN3 domain and belongs to the methyltransferase superfamily. Expressed in lung, brain, kidney, testis, mammary gland and cerebellum, BCDIN3 exists as a component of the multi-protein 7SK snRNP complex and functions as an S-adenosyl-L-methionine-dependent methyltransferase that stabilizes 7SK snRNA, specifically by adding a methylphosphate cap at the 5'-end of the snRNA.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: MEPCE polyclonal Antibody detects endogenous levels of MEPCE protein.
Molecular Weight: ~ 74kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: 7SK snRNA methylphosphate capping enzyme; MePCE; Bicoid-interacting protein 3 homolog; Bin3 homolog; MEPCE; BCDIN3
Immunogen: Recombinant full length Human MEPCE.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: