Metabotropic Glutamate Receptor 3 Antibody (C-term) [AMM06384G]

Metabotropic Glutamate Receptor 3 Antibody (C-term) [AMM06384G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This Metabotropic Glutamate Receptor 3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 828-857 amino acids from the C-terminal region of human Metabotropic Glutamate Receptor 3.

Cellular Localisation: Cell membrane; Multi-pass membrane protein

Molecular Weight: 98879

Clone: Polyclonal

Gene Name: GRM3

Gene ID: 2913

Function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.

Summary: Tissue Location: Detected in brain cortex, thalamus, subthalamic nucleus, substantia nigra, hypothalamus, hippocampus, corpus callosum, caudate nucleus and amygdala.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Metabotropic glutamate receptor 3, mGluR3, GRM3, GPRC1C, MGLUR3