Mevastatin | 1694

A HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase inhibitor. Cholesterol lowering drug. Inhibits the biosynthesis of isoprenoids; induces apoptosis by inhibition of post-translational prenylation of proteins such as Ras.

Mevastatin is a A HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase inhibitor. Cholesterol lowering drug.

1694 | Mevastatin DataSheet

Alternate Name/Synonyms: Compactin; ML-236B

Appearance: White solid

Formulation: N/A

CAS Number: 73573-88-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₃H₃₄O₅

Molecular Weight: 390.51

Cell-Permeable?: Yes

Purity: ≥95% by HPLC

Solubilities: DMSO (20 mg/ml) or Ethanol (25 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A HMG-CoA inhibitor

MDL Number: MFCD05662341

PubChem CID: 64715

SMILES: CCC(C)C(=O)OC1CCC=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O

InChi: InChI=1S/C23H34O5/c1-4-14(2)23(26)28-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-18-12-17(24)13-21(25)27-18/h6,8-9,14-15,17-20,22,24H,4-5,7,10-13H2,1-3H3/t14-,15-,17+,18+,19-,20-,22-/m0/s1

InChi Key: AJLFOPYRIVGYMJ-INTXDZFKSA-N