MGLL polyclonal Antibody | BS8329

MGLL polyclonal Antibody | BS8329 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB

Application Range: WB 1:500 - 1:2000

Background: Monoglyceride Lipase (MGL), also known as Lysophospholipase-like or Lysophospholipase homolog, is a ubiquitously expressed protein that functions in the endocannabinoid system. It is required for the the degradation of endocannabinoids and the complete hydrolysis of monoglycerides. In addition, Monoglyceride Lipase functions together with HSL (hormone-sensitive lipase) to hydrolyze intracellular triglyceride to glycerol and fatty acids. Monoglyceride Lipase is a presynaptic, cytosolic enzyme that functions as a serine hydrolase and specifically hydrolyzes 2- and 1 (3) -ester bonds of monoglycerides. In particular, Monoglyceride Lipase is responsible for the inactivation and degradation of 2-arachidonoylglycerol (2-AG) . 2-AG is a monoglyceride produced by neurons that activates cannabinoid receptors and possibly modulates neurotransmitter release and synaptic plasticity.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MGLL polyclonal Antibody detects endogenous levels of MGLL protein.

Molecular Weight: ~ 60 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Monoglyceride lipase; MGL; HU-K5; Lysophospholipase homolog; Lysophospholipase-like; Monoacylglycerol lipase; MAGL; MGLL

Immunogen: Recombinant full length Human MGLL.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: