MHC Class II Antibody [2G11] (FITC) | 99-279

MHC Class II Antibody [2G11] (FITC) | 99-279 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Chicken, Pigeon, Caiman

Homology: N/A

Immunogen: N/A

Research Area: Immunology

Tested Application: Flow

Application: MHC Class II Antibody [2G11] for use in flow cytometry and immunohistochemistry assays.

Specificiy: MHC Class II

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [2G11]

Isotype: IgG1

Conjugate: FITC

Physical State: Liquid

Buffer: Supplied in PBS/NaN3

Concentration: 0.5 mg/mL

Storage Condition: Store vial at 2-8˚C

Alternate Name: B-L

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The chicken major histocompatibility complex (MHC) , or B complex, consists of several clusters of highly polymorphic genes. Like their mammalian counterparts, the avian MHC exerts genetic influence over a variety of important biological functions such as immune response, disease resistance, growth and development, aging, and reproduction. Chicken MHC Class II genes, also known as the B-L subregion, of the chicken MHC encode cell surface glycoproteins that are homologous to mammalian Class II antigens. B-L antigens are structurally similar to mammalian Class II molecules in that they are noncovalently bound dimers of one heavy chain and one light chain. MHC Class II is primarily expressed on B cells and antigen presenting cells (APCs) .