MIB2 Antibody (N-Term) [APR33449G]

MIB2 Antibody (N-Term) [APR33449G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: M

Specificity: This MIB2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 216-249 amino acids from human MIB2.

Cellular Localisation: Cytoplasm. Endosome. Note=Colocalizes with endosomal compartments

Molecular Weight: 109939

Clone: Polyclonal

Gene Name: MIB2

Gene ID: 142678

Function: E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.

Summary: Tissue Location: Expressed in skeletal muscle, and to a lesser extent in heart, brain and kidney.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: E3 ubiquitin-protein ligase MIB2, 6.3.2.-, Mind bomb homolog 2, Novel zinc finger protein, Novelzin, Putative NF-kappa-B-activating protein 002N, Skeletrophin, Zinc finger ZZ type with ankyrin repeat domain protein 1, MIB2, SKD, ZZANK1