Mineralocorticoid receptor Polyclonal Antibody | E-AB-70260

Mineralocorticoid receptor Polyclonal Antibody | E-AB-70260 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Aldosterone receptor, MCR, MGC133092, Mineralocorticoid receptor, MLR, MR, NR3 C2, NR3C2, NR3C2 protein, Nuclear receptor subfamily 3 group C member 2

Application: WB

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Signal Transduction, Cardiovascular, Epigenetics and Nuclear Signaling

Background: This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.

Concentration: 1.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Mineralocorticoid receptor

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 107 kDa

Molecular Weight(Observed): 107 kDa