MIP-1alpha, murine recombinant | 4245

Murine macrophage inflammatory protein-1 (MIP-1) is an 7.8 kDa protein containing 69 amino acid residues. It is part of the CC chemokine family and plays an important role in the inflammatory response of blood monocytes and tissue microphages.

4245 | MIP-1alpha murine recombinant DataSheet

Biomolecule/Target: MIP-1 alpha

Synonyms: Small inducible cytokine A3, CCL3, Macrophage inflammatory protein 1-, MIP-1-, Tonsillar lymphocyte LD78 protein, G0/G1 switch regulatory protein 19-1, G0S19-1 protein, SIS-, PAT 464,1, chemokine (C-C motif) ligand 3, MIP1A, SCYA3, G0S19-1, LD78, TY-5, SIS-, Heparin-binding chemotaxis protein, L2G25B,

Alternates names: Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen, VEGF, MGC70609.

Taglines: Recruits and activates polymorphonuclear leukocytes

NCBI Gene ID #: 7422

NCBI Gene Symbol: VEGFA

Gene Source: Human

Accession #: P15692

Recombinant: Yes

Source: Human 293 cell expressed

Purity by SDS-PAGEs: > 95%

Assay: SDS-PAGE

Purity: 99%

Assay #2: HPLC

Endotoxin Level:

Activity (Specifications/test method): The activity was determined by the dose-dependent stimulation of the proliferation of EA.hy926 human endothelial cells with EC50 600 ng/ml.

Biological activity: EC50 is 600 ng/ml. The activity was determined by the dose-dependent stimulation of the proliferation of EA.hy926 human endothelial cells.

Results: 600 ng/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 45 kDa, homodimer, glycosylated

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Sterile filtered and lyophilized with no additives

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute at 0.2-0.3 mg/mL in distilled water is recommended.

Amino acid sequence: N/A