MITF Polyclonal Antibody | E-AB-60287

MITF Polyclonal Antibody | E-AB-60287 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: MITF, CMM8, COMMAD, MI, WS2, WS2A, bHLHe32

Application: WB

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Immunology

Background: This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human MITF (NP_937801.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 40 kDa/46 kDa/52 kDa/55 kDa/56 kDa/57 kDa/58 kDa

Molecular Weight(Observed): 65 kDa