MKKS Antibody (C-term) [APR04091G]

MKKS Antibody (C-term) [APR04091G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This MKKS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 408-437 amino acids from the C-terminal region of human MKKS.

Cellular Localisation: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytosol Nucleus. Note=The majority of the protein resides within the pericentriolar material (PCM), a proteinaceous tube surrounding centrioles. During interphase, the protein is confined to the lateral surfaces of the PCM but during mitosis it relocalizes throughout the PCM and is found at the intercellular bridge. The MKSS protein is highly mobile and rapidly shuttles between the cytosol and centrosome

Molecular Weight: 62342

Clone: Polyclonal

Gene Name: MKKS (HGNC:7108)

Gene ID: 8195

Function: Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis (PubMed:20080638) . Plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638) . May play a role in protein processing in limb, cardiac and reproductive system development. May play a role in cytokinesis (PubMed:28753627) .

Summary: Tissue Location: Widely expressed in adult and fetal tissues.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin, Bardet-Biedl syndrome 6 protein, MKKS, BBS6