ML239 | 2696

ML239 is a selective inhibitor of breast cancer stem cells. It inhibits cancer stem cells with an IC₅₀ of 1.16 μM with 24-fold selectivity against the control cell line. ML239 alters the expression of genes in the MAPK, NF-κB, and inflammatory cytokine pathways.

ML239 is a selective inhibitor of breast cancer stem cells. It inhibits cancer stem cells with an IC₅₀ of 1.16 μM with 24-fold selectivity against the control cell line. ML239 alters the expression of genes in the MAPK, NF-κB, and inflammatory cytokine pathways.

2696 | ML239 DataSheet

Alternate Name/Synonyms: N'-[(Z)-pyrrol-2-ylidenemethyl]-2-(2,4,6-trichlorophenoxy)acetohydrazide; (2,4,6-Trichlorophenoxy)-acetic acid (1H-pyrrol-2-ylmethylene)-hydrazide; CID-49843203

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 1378872-36-6

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₃H10Cl₃N₃O₂

Molecular Weight: 346.6

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~15 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A selective inhibitor of breast cancer stem cell

MDL Number: MFCD23098913

PubChem CID: 49843203

SMILES: C1=CC(=CNNC(=O)COC2=C(C=C(C=C2Cl)Cl)Cl)N=C1

InChi: InChI=1S/C13H10Cl3N3O2/c14-8-4-10(15)13(11(16)5-8)21-7-12(20)19-18-6-9-2-1-3-17-9/h1-6,18H,7H2,(H,19,20)/b9-6-

InChi Key: SZYDKEIZVCSYNB-TWGQIWQCSA-N