A highly selective K⁺- ionophore. It binds potassium ions (K⁺) and facilitates their transfer across lipid bilayers. Inhibits Ca²⁺-ATPase activity and promotes cell death by mitochondrial swelling...
MLN-8054 is a potent and selective inhibitor of Aurora kinase A (IC₅₀ = 4 nM). Displays 40-fold selectivity for Aurora A over Aurora B.MLN-8054 is a potent and selective inhibitor of Aurora kinase A...
MLN-9708 is a prodrug of Ixazomib citrate (MLN-2238). MLN-9708 is an orally bioavailable next-generation proteasome inhibitor (PI) with potential potent anticancer activity in both hematologic and...