MLPH polyclonal Antibody | BS8330

MLPH polyclonal Antibody | BS8330 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB,IHC,IF

Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Background: Slac2-a (for synaptotagmin-like protein (Slp) homolog lacking C2 domains-a) links Rab27A on melanosomes with Myosin VA in melanocytes. Slac2-a binds Myosin VA through a C-terminal region and GTP-bound Rab27A through its synaptotagmin-like protein homology domain (SHD), which is located near the N-terminus. The transport of pigment and cytotoxic granules in melanocytes requires the stable formation of this complex, and thus mutations in the binding domains of the three protein components may cause albinism and/or severe immune disorders.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MLPH polyclonal Antibody detects endogenous levels of MLPH protein.

Molecular Weight: ~ 75 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Melanophilin; Exophilin-3; Slp homolog lacking C2 domains a; SlaC2-a; Synaptotagmin-like protein 2a; MLPH; SLAC2A

Immunogen: Recombinant full length Human MLPH.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: