MMP-1 polyclonal Antibody | BS90866

MMP-1 polyclonal Antibody | BS90866 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB ICC IHC

Application Range: WB:1:1,000 ICC:1:200 IHC:1:200

Background: MMP-1 has an archetypal structure consisting of a pre-domain, a pro-domain, a catalytic domain, a linker region and a hemopexin-like domain. Two main nomenclatures for the primary structure are currently in use, the original one from which the first amino-acid starts with the signalling peptide and a second one where the first amino-acid starts counting from the prodomain (proenzyme nomenclature) . MMPs are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Specifically, MMP-1 breaks down the interstitial collagens, types I, II, and III. Mechanical force may increase the expression of MMP1 in human periodontal ligament cells.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: MMP-1 polyclonal Antibody detects endogenous levels of MMP-1 protein.

Molecular Weight: 54 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: MMP-1, 27 kDa interstitial collagenase, CLG, CLGN, collagenase, fibroblast, collagenase, interstitial, Fibroblast collagenase, Interstitial collagenase, Matrix metallopeptidase 1 (interstitial collagenase), Matrix metalloprotease 1, Matrix Metalloproteinase 1, Matrix metalloproteinase-1, MMP 1, MMP-1, MMP1, MMP1, OTTHUMP00000045866,

Immunogen: peptide

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Peptide affinity purified

Pathway: