MMP-13 polyclonal Antibody | BS90868

MMP-13 polyclonal Antibody | BS90868 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Application: WB ICC/IF IHC FC

Application Range: WB:1:1,000 ICC:1:100-1:500 IHC:1:50-1:200 FC:1:50-1:100

Background: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB) . MMP catalysis requires both calcium and zinc. MMP-13 (also designated collagenase-3) is produced by breast carcinomas and degrades collagen types I, II and III. MMP-13 has wide substrate specificity, and its physiologic expression is limited to situations in which rapid and effective remodeling of collagenous ECM takes place, such as fetal bone development and adult bone remodeling.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: MMP-13 polyclonal Antibody detects endogenous levels of MMP-13 protein.

Molecular Weight: 54 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: MMP-13, MMP13, CLG 3, CLG3, Collagenase 3, Collagenase3, MANDP1, Matrix metallopeptidase 13 (collagenase 3), Matrix Metalloproteinase 13, Matrix metalloproteinase-13, MMP 13, MMP-13, Mmp13, MMP13,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: