Description
NFF-3 is a useful fluorogenic substrate for MMP-3 (stromelysin 1). NFF-3 is hydrolyzed rapidly by MMP-3 (kcat/Km = 218,000 s-1 M-1) and very slowly by MMP-9 (kcat/Km = 10,100 s-1 M-1), but no significant hydrolysis by MMP-1 and MMP-2.
NFF-3 is a useful fluorogenic substrate for MMP-3 (stromelysin 1). NFF-3 is hydrolyzed rapidly by MMP-3 (kcat/Km = 218,000 s-1 M-1) and very slowly by MMP-9 (kcat/Km = 10,100 s-1 M-1), but no significant hydrolysis by MMP-1 and MMP-2.
B1060 | MMP-3 Substrate, NFF-3 DataSheet
Alternate Name/Synonyms: NFF-3; Mca - RPKPVE - Nva - WR - K(Dnp) - NH2
Appearance: Lyophilized yellow solid
Formulation: N/A
CAS Number: 158584-09-9
Structure Available?: N/A
Peptide sequence: Mca - Arg - Pro - Lys - Pro - Val - Glu - Nva - Trp - Arg - Lys(Dnp) - NH2
Salt Form: No
Molecular Formula: C₇₈H₁₁₀N₂₂O₂0
Molecular Weight: 1675.84
Cell-Permeable?: Yes
Purity: ≥95% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A useful fluorogenic substrate for MMP-3 (stromelysin 1)
MDL Number: N/A
PubChem CID: 16131108
SMILES: CCCC(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCNC3=C(C=C(C=C3)[N+](=O)[O-])[N+](=O)[O-])C(=O)N)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)C)NC(=O)C4CCCN4C(=O)C(CCCCN)NC(=O)C5CCCN5C(=O)C(CCCNC(=N)N)NC(=O)CC6=CC(=O)OC7=C6C=CC(=C7)OC
InChi: CCC[C@@H](C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCNC3=C(C=C(C=C3)[N+](=O)[O-])[N+](=O)[O-])C(=O)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CCCCN)NC(=O)[C@@H]5CCCN5C(=O)[C@H](CCCNC(=N)N)NC(=O)CC6=CC(=O)OC7=C6C=CC(=C7)OC
InChi Key: TVZDWYYXHAIMCR-BKNSPTOHSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |