MMP-7 polyclonal Antibody | BS6059

MMP-7 polyclonal Antibody | BS6059 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC

Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200

Background: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB) . MMP catalysis requires both calcium and zinc. MMP-7 (also designated Pump-1, matrilysin or uterine metalloproteinase) degrades casein, fibronectin and gelatin types I, III, IV and V. MMP-7 mRNA is produced exclusively by epithelial cells in mouse and expression is restricted to specific organs, suggesting that in addition to matrix degradation and remodeling, MMP-7 may be involved in the differentiated function of these organs.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MMP7 polyclonal Antibody detects endogenous levels of MMP7 protein.

Molecular Weight: ~ 30 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Matrilysin; Matrilysin uterine; Matrin; Matrix Metalloproteinase 7; Matrix metalloproteinase-7; MMP 7; MMP-7; MMP7; MMP7; MPSL1; PUMP 1; Pump 1 protease; Pump-1 protease; PUMP1; Uterine Matrilysin; Uterine metalloproteinase;

Immunogen: Recombinant full length Human MMP-7.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: