Description
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-9 has been shown to degrade bone collagens in concert with MMP-1 (also designated interstitial collagenase, fibroblast collagenase or collagenase-1), and cysteine proteases and may play a role in bone osteoclastic resorption.
3969 | MMP-9 Antibody DataSheet
Antibody Target: MMP-9
Target Alternative Name: GELB , EC 3.4.24.35 , CLG4B , Matrix metalloproteinase
Tag Line:
Category: MMP
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Human
Immunogen Sequence: E. coli-expressed recombinant human MMP-9
Accession #: AAM97934
Gene ID: 4318
Appearance: Colorless liquid
Form: Liquid
Concentration: 0.5 mg/ml
Formulation: 200 µg (0.5 mg/ml) affinity purified rabbit anti-human MMP-9 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5mM EDTA and 0.01% thimerosal.
Purification: Affinity purified
Application: Western blot
Positive Control: Recombinant human MMP-9
Application And Usages: The antibody can be used in Western Blot analysis (1-4 µg/ml). However, the optimal conditions should be determined individually. Recombinant human MMP-9 (Cat.# 7789-10) can be used as a positive control.
Country of Animal Origin: China
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: Verified
Immunocytochemistry Verified: Not Verified
Immunofluorescence Verified: Not Verified
Immunoprecipitation Verified: Not Verified
FACS Verified: Not Verified
ELISA Verified: Not Verified
ChIP Verified: Not Verified
Dot Blot Verified:
Flow Cytometry Verified: Not Verified
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |