Description
Cell-permeable. A potent inhibitor of matrix metalloproteinase-3 (MMP-3)( Ki = 0.013 µM). Also inhibits MMP-1, -2, -7-10, -12-14 and MMP-20. Attenuates inflammation-induced thermal hyperalgesia.
NNGH is a potent inhibitor of matrix metalloproteinase-3 (MMP-3)( Ki = 0.013 µM). Also inhibits MMP-1, -2, -7-10, -12-14 and MMP-20. Attenuates inflammation-induced thermal hyperalgesia.
2569 | MMP-III Inhibitor, NNGH DataSheet
Alternate Name/Synonyms: N-Isobutyl-N-(4-methoxyphenylsulfonyl)glycyl hydroxamic acid
Appearance: White solid
Formulation: N/A
CAS Number: 161314-17-6
Structure Available?: Y
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₃H₂₀N₂O₅S
Molecular Weight: 316.38
Cell-Permeable?: Yes
Purity: ³98% by TLC
Solubilities: DMSO (~25 mg/ml) or EtOH (~ 25 mg/ml
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent MMP-III inhibitor
MDL Number: MFCD02179370
PubChem CID: 448002
SMILES: CC(C)CN(CC(NO)=O)S(C1=CC=C(OC)C=C1)(=O)=O
InChi: InChI=1S/C13H20N2O5S/c1-10(2)8-15(9-13(16)14-17)21(18,19)12-6-4-11(20-3)5-7-12/h4-7,10,17H,8-9H2,1-3H3,(H,14,16)
InChi Key: JIRXORZYIXSWOB-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24 months |