MMP11 Polyclonal Antibody | E-AB-12573

MMP11 Polyclonal Antibody | E-AB-12573 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Matrix Metalloproteinase 11, Matrix metalloproteinase-11, MMP-11, Mmp11, MMP11, SL 3, SL-3, SL3, ST3, STMY3, Stromelysin 3, Stromelysin III, Stromelysin-3

Application: WB, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Cardiovascular, Signal Transduction

Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.

Concentration: 0.4 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human MMP11

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 55 kDa

Molecular Weight(Observed): N/A