MMP2 Polyclonal Antibody | E-AB-40409

MMP2 Polyclonal Antibody | E-AB-40409 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 72 kDa gelatinase, CLG4, CLG4A, Collagenase Type 4 alpha, Gelatinase A, Matrix Metalloproteinase 2, MMP 2, MONA, Neutrophil gelatinase, PEX, TBE 1

Application: WB, IHC

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cardiovascular, Cancer, Cell Biology, Metabolism

Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response.

Concentration: 0.7 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant Human 72 kDa type IV collagenase protein

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3

Purification Method: Antigen Affinity Purification

Dilution: WB 1:500-1:2000 IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 65, 68, 73 kDa

Molecular Weight(Observed): 68 kDa