MN1 (K850) polyclonal Antibody | BS2560

MN1 (K850) polyclonal Antibody | BS2560 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: The MN1 gene, which resides on chromosome 22, encodes a 1,319 amino acid protein. The ETV6/TEL gene has been reported to fuse to MN1. The MN1-TEL fusion protein, encoded by the translocation (12;22) (p13;q11) in myeloid leukemia, is a transcription factor with transforming activity. Defects in MN1 (meningioma 1) may be a cause of meningiomas, slowly growing benign tumors derived from the arachnoidal cap cells of the leptomeninges, the soft coverings of the brain and spinal cord.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MN1 (K850) pAb detects endogenous levels of MN1 protein.

Molecular Weight: ~ 135 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Probable tumor suppressor protein MN1; MN1

Immunogen: Synthetic peptide, corresponding to amino acids 830-880 of Human MN1.

Conjugate: N/A

Modification: N/A

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A