MOCOS Polyclonal Antibody | E-AB-66270

MOCOS Polyclonal Antibody | E-AB-66270 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: MOCOS, HMCS, MCS, MOS, XAN2

Application: WB

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: N/A

Background: This gene encodes an enzyme that sulfurates the molybdenum cofactor which is required for activation of the xanthine dehydrogenase (XDH) and aldehyde oxidase (AO) enzymes. XDH catalyzes the conversion of hypoxanthine to uric acid via xanthine, as well as the conversion of allopurinol to oxypurinol, and pyrazinamide to 5-hydroxy pyrazinamide. Mutations in this gene cause the metabolic disorder classical xanthinuria type II which is characterized by the loss of XDH/XO and AO enzyme activity, decreased levels of uric acid in the urine, increased levels of xanthine and hypoxanthine in the serum and urine, formation of xanthine stones in the urinary tract, and myositis due to tissue deposition of xanthine.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human MOCOS (NP_060417.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 98 kDa

Molecular Weight(Observed): 98 kDa