MOGS Antibody | 14-601

MOGS Antibody | 14-601 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 60-320 of human MOGS (NP_006293.2) .

Research Area: Other

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: U-87MG

Positive Control 2: LO2

Positive Control 3: BxPC-3

Positive Control 4: OVCAR-3

Positive Control 5: Mouse Brain

Positive Control 6: Mouse Liver

Molecular Weight: Observed: 80kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: GCS1, DER7, GCS1, CDG2B, CWH41

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1, 2-linked glucose residue from the Glc (3) -Man (9) -GlcNAc (2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb) . Two transcript variants encoding different isoforms have been found for this gene.