Description
Mouse Anti-Human CD105/Endoglin, Antagonistic Antibody | mT1001m-h | Gentaur UK, US & Europe Distribution
Species: Anti-Human
Host / biotech: Mouse
Comment: N/A
Label: N/A
Clone / Antibody feature: (#7D11)
Subcategory: Monoclonal Antibody
Category: Antibody
Synonyms: Endoglin; END; ORW; HHT1; ORW1; CD105
Isotype: IgG1
Application: Blocking TGF-beta1 induced threonine/serine phosphorylation of endoglin
Detection Range: N/A
Species Reactivity/Cross reactivity: Human
Antigen: human endoglin extra-cellular domain
Description: Endoglin, also known as CD105, is a type I integral transmembrane glycoprotein and is an accessory receptor for TGF-beta superfamily ligands. Endoglin is highly expressed on vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. It is also found on activated monocytes, mesenchymal stem cells and leukemic cells of lymphoid and myeloid lineages.
Purity Confirmation: N/A
Endotoxin: N/A
Formulation: lyophilized
Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Reconstituation: Centrifuge the vial prior to opening. Reconstitute the antibody with 400 µl sterile PBS and the final concentration is 500 µg/ml.
Molecular Weight: N/A
Lenght (aa): N/A
Protein Sequence: N/A
NCBI Gene ID: 2022