Mouse Anti-Human CD105/Endoglin Antibody | 101-M160

Mouse Anti-Human CD105/Endoglin Antibody | 101-M160 | Gentaur UK, US & Europe Distribution

Species: Anti-Human

Host / biotech: Mouse

Comment: N/A

Label: N/A

Clone / Antibody feature: (#12J11)

Subcategory: Monoclonal Antibody

Category: Antibody

Synonyms: Endoglin; END; ORW; HHT1; ORW1; CD105

Isotype: IgG1

Application: IHC

Detection Range: N/A

Species Reactivity/Cross reactivity: Human

Antigen: cell membrane glycoproteins of lymphoblastic leukemia cells

Description: CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF-ß1 and ß3 with high affinity but not to TGF-ß2.

Purity Confirmation: N/A

Endotoxin: N/A

Formulation: lyophilized

Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Molecular Weight: N/A

Lenght (aa): N/A

Protein Sequence: N/A

NCBI Gene ID: 2022