Mouse Anti-Human Fetuin-B Antibody | 101-M399

Mouse Anti-Human Fetuin-B Antibody | 101-M399 | Gentaur UK, US & Europe Distribution

Species: Anti-Human

Host / biotech: Mouse

Comment: N/A

Label: N/A

Clone / Antibody feature: (#6N19)

Subcategory: Monoclonal Antibody

Category: Antibody

Synonyms: FETUB; 16G2; Gugu; IRL685

Isotype: IgG1

Application: WB

Detection Range: N/A

Species Reactivity/Cross reactivity: Human

Antigen: recombinant human Fetuin-B

Description: Fetuins are members of the cystatin superfamily of cysteine protease inhibitors. Additional members of this superfamily are kininogen and histidine-rich glycoprotein. Fetuin A and B are two known members of the fetuin family. Hepatocytes are believed to be the principal cellular source, but other cell types also express it. Fetuin A, also known as α2-Heremans-Schmid glycoprotein, is an inhibitor of basic calcium phosphate precipitation and a negative acutephase protein. Normal circulating levels of Fetuin A in adults (300-600 ug/mL) fall significantly (30-50%) during injury and infection. Fetuin A and B display similarities and differences in their characteristics. Fetuin B exhibits reduction of calcification, while both mRNA levels were downregulated during the acute phase in inflammation-induced rats. However, they share only 20% amino acid sequence identity. The amounts of Fetuin B in human serum, unlike Fetuin A, vary with gender and are higher in females than in males.

Purity Confirmation: N/A

Endotoxin: N/A

Formulation: lyophilized

Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Molecular Weight: N/A

Lenght (aa): N/A

Protein Sequence: N/A

NCBI Gene ID: 26998