Mouse Anti-Human FGF-19 Antibody | 101-M406

Mouse Anti-Human FGF-19 Antibody | 101-M406 | Gentaur UK, US & Europe Distribution

Species: Anti-Human

Host / biotech: Mouse

Comment: N/A

Label: N/A

Clone / Antibody feature: (#4G16)

Subcategory: Monoclonal Antibody

Category: Antibody

Synonyms: FGF19

Isotype: IgG1

Application: WB, IHC (P)

Detection Range: N/A

Species Reactivity/Cross reactivity: Human

Antigen: Recombinant human FGF-18

Description: Human FGF19 cDNA predicts a 251 aa precursor protein with a 22 aa signal peptide and a 229 aa secreted mature protein with no potential N-linked glycosylation sites. Among FGF family members, human FGF19 is most closely related to chicken FGF19 and murine FGF15, sharing approximately 61% and 51% aa sequence identity, respectively. Neither the human orthologue of mouse FGF15, nor the mouse counterpart of human FGF19 has been identified. With the exception of adult gall bladder epithelium, FGF19 expression is restricted to fetal tissues. Unlike most FGFs which bind to and activate more than one FGF receptor, FGF19 is a specific ligand for FGF R4. Similarly, another FGF family member, FGF7 (KGF), only activates KGF R, the IIIb isoform of FGF R2. During chick embryogenesis, FGF19 has been shown to act synergistically with Wnt8c to initiate inner ear development.

Purity Confirmation: N/A

Endotoxin: N/A

Formulation: lyophilized

Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Molecular Weight: N/A

Lenght (aa): N/A

Protein Sequence: N/A

NCBI Gene ID: 9965