Mouse Anti-Human GDNF R alpha 4 Antibody | 101-M440

Mouse Anti-Human GDNF R alpha 4 Antibody | 101-M440 | Gentaur UK, US & Europe Distribution

Species: Anti-Human

Host / biotech: Mouse

Comment: N/A

Label: N/A

Clone / Antibody feature: (#3P34)

Subcategory: Monoclonal Antibody

Category: Antibody

Synonyms: glial cell line derived neurotrophic factor Receptor alpha 4

Isotype: IgG1

Application: WB

Detection Range: N/A

Species Reactivity/Cross reactivity: Human

Antigen: recombinant human GDNF-Ralpha4

Description: GDNF family receptor alpha-1 is a protein that in humans is encoded by the GFRA1 gene. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Purity Confirmation: N/A

Endotoxin: N/A

Formulation: lyophilized

Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Molecular Weight: N/A

Lenght (aa): N/A

Protein Sequence: N/A

NCBI Gene ID: 64096