Mouse Anti-Human MCP-4 Antibody | 101-M76

Mouse Anti-Human MCP-4 Antibody | 101-M76 | Gentaur UK, US & Europe Distribution

Species: Anti-Human

Host / biotech: Mouse

Comment: N/A

Label: N/A

Clone / Antibody feature: N/A

Subcategory: Monoclonal Antibody

Category: Antibody

Synonyms: CCL13; NCC1; CKb10; MCP-4; NCC-1; SCYL1; SCYA13

Isotype: IgG1, kappa

Application: ELISA, WB, N

Detection Range: N/A

Species Reactivity/Cross reactivity: Human

Antigen: Recombinant Human MCP-4

Description: Monocyte Chemoattractant Protein-4 (MCP-4), is a CC chemokine that acts as a chemoattractant for monocytes, eosinophils and T cells and as an activator of basophils. Human MCP-4/CCL13 cDNA encodes a 98 amino acid residue precursor protein with a 23 amino acid residue hydrophobic signal peptide that is cleaved to yield an 8 kDa, 75 aa mature CCL13. Mature MCP-4 lacks any potential N-glycosylation sites and shares a pyroglutamate proline motif with other human MCP proteins. Human MCP-4 is most homologous to MCP-1, -3 and Eotaxin, exhibiting approximately 65-66% amino acid sequence identity. CCL13 or MCP-4 mRNA is expressed by a number of activated cell types, including endothelial cells, macrophages, bronchial epithelium and type II alveolar cells, and perhaps lymphocytes. The bioactivities of MCP-4 are mediated by the CC chemokine receptors CCR2 and CCR3.

Purity Confirmation: N/A

Endotoxin: N/A

Formulation: lyophilized from PBS

Storage Handling Stability: The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.

Reconstituation: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

Molecular Weight: N/A

Lenght (aa): N/A

Protein Sequence: N/A

NCBI Gene ID: 6357