Description
Mouse Anti-Human NGF-beta Antibody | 101-M168/101-M582 | Gentaur UK, US & Europe Distribution
Species: Anti-Human
Host / biotech: Mouse
Comment: N/A
Label: N/A
Clone / Antibody feature: N/A
Subcategory: Monoclonal Antibody
Category: Antibody
Synonyms: NGF; NGFB; HSAN5; Beta-NGF
Isotype: IgG1
Application: ELISA, N, WB, IHC
Detection Range: N/A
Species Reactivity/Cross reactivity: Human
Antigen: Recombinant Human NGF-beta
Description: β-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. β-NGF is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. β-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. The functional form of human β-NGF is a noncovalently disulfide-linked homodimer, of two 14 kDa polypeptide monomers (240 total amino acid residues). The three disulfide bonds are required for biological activity.
Purity Confirmation: N/A
Endotoxin: N/A
Formulation: lyophilized from PBS
Storage Handling Stability: The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Reconstituation: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Molecular Weight: N/A
Lenght (aa): N/A
Protein Sequence: N/A
NCBI Gene ID: 4803