Description
Mouse Anti-Human NKG2D Antibody | 101-M585 | Gentaur UK, US & Europe Distribution
Species: Anti-Human
Host / biotech: Mouse
Comment: N/A
Label: N/A
Clone / Antibody feature: (#10R27)
Subcategory: Monoclonal Antibody
Category: Antibody
Synonyms: KLRK1; KLR; CD314; NKG2D; NKG2-D; D12S2489E
Isotype: IgG2
Application: WB, FC
Detection Range: N/A
Species Reactivity/Cross reactivity: Human
Antigen: recombinant human NKG2D
Description: NKG2D is a type II transmembrane protein with an extracellular C-type lectin domain. It occurs as a disulfide-linked homodimer that associates with either the DAP12 or DAP10 transmembrane adapter proteins. NKG2D is expressed on NK cells and some T cell subsets, where it functions as an activating receptor to trigger cytolytic activity and cytokine secretion. Ligands for human NKG2D include MICA, MICB, and ULBP-1, -2, -3, and -4. Mouse NKG2D ligands include H60, MULT-1, and Rae-1 alpha, beta, gamma, delta, and epsilon.
Purity Confirmation: N/A
Endotoxin: N/A
Formulation: lyophilized
Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Molecular Weight: N/A
Lenght (aa): N/A
Protein Sequence: N/A
NCBI Gene ID: 22914